Numerous intrusions of mafites and ultramafites are revealed in the frame of the Buki massif (the Ukrainian Shield). The epigenetic impregnated sulphide copper-nickel ores were found in two of them (Prutivka and Zaliznyaki). The chemistry of these intrusions is compared with intrusions of similar composition in nickel-bearing regions of the Soviet Union. A conclusion was made about the potential sulfide nickel mineralization of the massifs composed of pyroxenites and peridotites, which have positive petrochemical signs for the ores.